Product Description
| Cat Number | T0153 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | Oltipraz (RP 35972) is a synthetic dithiolethione with potential chemopreventive and anti-angiogenic properties. Oltipraz induces phase II detoxification enzymes, such as glutathione S transferase (GST) and NAD(P)H: quinone oxidoreductase 1 (NQO1). The induction of detoxification enzymes enhances the detoxification of certain cancer-causing agents, thereby enhancing their elimination and preventing carcinogen-induced DNA damages. Although the exact mechanism through which the anti-angiogenesis effect remains to be fully elucidated, oltipraz maybe able to modulate the expression of a number of angiogenic factors, thereby blocking the sustained and focal neovascularization in multiple tumor cell types. |
| Molecular Weight | 226.34 |
| Purity | 0.9956 |
| Formula | C8H6N2S3 |
| Smiles | CC1=C(SSC1=S)C1=NC=CN=C1 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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