Human IFN gamma R1/IFNGR1 Protein (IFN-HM2GR)
SKU: BTL-KB-P-01838 |
Host: Human |
Brand: Kactus Bio
Product Description
| Cat Number | IFN-HM2GR |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Human IFN gamma R1/IFNGR1 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Glu18-Gly245. |
| Target | IFN gamma R1/IFNGR1 |
| Host | Human |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | IFN-gamma and one of its receptor subunits, IFNGR1, are translocated to the nucleus, together with STAT1alpha as one macromolecular complex, via the classical importin-dependent pathway.Put IFN-gamma and its receptor subunit, IFNGR1, in direct contact with the promoter region of IFN-gamma-activated genes with associated increased activity, thus suggesting a transcriptional/cotranscriptional role for IFN-gamma/IFNGR1 as well as a possible role in determining the specificity of IFN-gamma action. |
| Molecular Mass | The protein has a predicted MW of 52.4 kDa. Due to glycosylation, the protein migrates to 60-75 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Glu18-Gly245 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | AAH05333 |
| Amino Acid Sequence | Recombinant Human IFN gamma R1/IFNGR1 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Glu18-Gly245. |
| Storage | -20 to -80°C for 24 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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