Product Description
| Cat Number | HY-156961 |
|---|---|
| Category | Reference compound |
| Pack Size | 1 EA |
| Description | GLPG3667 is a reversible, ATP-competitive and orally active TYK2 inhibitor with an IC 50 of 2.3 nM. GLPG3667 inhibits IFNα/pSTAT1, and the IC 50 values in human peripheral blood mononuclear cell (PBMC) and whole blood assays are 70 nM and 623 nM, respectively. GLPG3667 has the potential for the study of inflammatory and autoimmune diseases [1] . |
| Molecular Weight | 443.46 |
| Research Field | Inflammation/Immunology |
| Purity | 99.81 |
| Formula | C22H21N9O2 |
| Smiles | N#CC1=NC=C(C(C)=C1)OC2=CC(NC3=NN=C(N4CCOCC4)C=C3)=C(N=CN5C)C5=N2 |
| Scientific Background | Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt |
| Storage | -20°C, 3 years; 4°C, 2 years (Powder) |
| View Document | |
| Note | The product is for research use only |
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