Human GHR/Growth Hormone R Protein (GHR-HM101)
SKU: BTL-KB-P-01659 |
Host: Human |
Brand: Kactus Bio
Product Description
| Cat Number | GHR-HM101 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Human GHR/Growth Hormone R Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala27-Tyr264. |
| Target | GHR/Growth Hormone R |
| Host | Human |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | Pegvisomant, a growth hormone receptor (GHR) antagonist, is a well-known drug that was designed to treat acromegaly. However, recent studies have indicated that the GHR is a "moonlighting" protein that may exhibit dual functions based on its localization in the plasma membrane and nucleus. |
| Molecular Mass | The protein has a predicted MW of 28.8 kDa. Due to glycosylation, the protein migrates to 45-60 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Ala27-Tyr264 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | P10912-1 |
| Amino Acid Sequence | Recombinant Human GHR/Growth Hormone R Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala27-Tyr264. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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