GLP-1R Antibody
SKU: BTL-AB-A-17302 |
Host: Polyclonal, Rabbit IgG |
Brand: Assay Biotech
Product Description
| Cat Number | G273 |
|---|---|
| Category | Primary Antibody |
| Pack Size | 50 μl, 100 μl |
| Description | glucagon like peptide 1 receptor(GLP1R) Homo sapiens This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016], |
| Applications | WB, IF, ELISA |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GLP1R. AA range:101-150 |
| Clonality | Polyclonal |
| Specificity | GLP-1R Polyclonal Antibody detects endogenous levels of GLP-1R protein. |
| Host | Polyclonal, Rabbit IgG |
| Modification | Unmodified/Total |
| Dilution Range | WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications. |
| Purity | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | The product is for research use only |
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