Human FGFR1 alpha (IIIc) Protein (FGF-HM1RA)
SKU: BTL-KB-P-01432 |
Host: Human |
Brand: Kactus Bio
Product Description
| Cat Number | FGF-HM1RA |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Human FGFR1 alpha (IIIc) Protein is expressed from HEK293 with His tag at the C-terminus.It contains Arg22-Glu374. |
| Target | FGFR1 alpha (IIIc) |
| Host | Human |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | Fibroblast growth factors (FGFs) comprise a family of at least eighteen structurally related proteins that are involved in a multitude of physiological and pathological cellular processes, including cell growth, differentiation, angiogenesis, wound healing and tumorgenesis. The biological activities of the FGFs are mediated by a family of type I transmembrane tyrosine kinases which undergo dimerization and autophosphorylation after ligand binding.FGFR1 is tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and correct axial organization during embryonic development, normal skeletogenesis and normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. |
| Molecular Mass | The protein has a predicted MW of 40.74 kDa. Due to glycosylation, the protein migrates to 65-80 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Arg22-Glu374 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 0.1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | P11362-7 |
| Amino Acid Sequence | Recombinant Human FGFR1 alpha (IIIc) Protein is expressed from HEK293 with His tag at the C-terminus.It contains Arg22-Glu374. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | The product is for research use only |
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