Human FAM171A2 Protein (FAM-HM1A2)
SKU: BTL-KB-P-01362 |
Host: Human |
Brand: Kactus Bio
Product Description
| Cat Number | FAM-HM1A2 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Human FAM171A2 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Lys30-Thr315. |
| Target | FAM171A2 |
| Host | Human |
| Purity | > 95% as determined by Bis-Tris PAGE |
| Scientific Background | The FAM171A2 gene encodes a transmembrane protein, it is implicated in signaling, vesicle trafficking, and interactions with the extracellular matrix. According to the Human Protein Atlas, it is predicted to localize to the membrane, and recent data suggests interaction with DYNLL1 (Dynein Light Chain LC8-Type 1), implying a role in intracellular transport mechanisms. Emerging studies indicate that FAM171A2 may act as a neuronal receptor involved in the endocytosis of pathological α-synuclein fibrils. Overexpression of FAM171A2 promotes uptake and propagation of these fibrils, while neuronal knockdown exhibits protective effects. |
| Molecular Mass | The protein has a predicted MW of 32.42 kDa. Due to glycosylation, the protein migrates to 42-52 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Lys30-Thr315 |
| Appearance | Liquid |
| Endotoxin Levels | Less than 0.1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | A8MVW0 |
| Amino Acid Sequence | Recombinant Human FAM171A2 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Lys30-Thr315. |
| Storage | Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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