Product Description
| Cat Number | AT2208a |
|---|---|
| Category | Primary Antibody |
| Pack Size | 100 µg |
| Description | The GLP2 receptor (GLP2R) is a G protein-coupled receptor superfamily member closely related to the glucagon receptor ans GLP1 receptor. Glucagon-like peptide-2 (GLP2) is a 33-amino acid proglucagon-derived peptide produced by intestinal enteroendocrine cells. Like glucagon-like peptide-1 (GLP1) and glucagon itself, it is derived from the proglucagon peptide encoded by the GCG gene. GLP2 stimulates intestinal growth and upregulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. Moreover, GLP2 prevents intestinal hypoplasia resulting from total parenteral nutrition. GLP2R, a G protein-coupled receptor superfamily member is expressed in the gut and closely related to the glucagon receptor (GCGR) and the receptor for GLP1 (GLP1R). |
| Applications | WB, E |
| Immunogen | Recombinant Protein |
| Immunogen Speice | Human: ~~ Positive |
| Clonality | Monoclonal |
| Clone | 1F2 |
| Gene | GLP2R |
| Synonyms | Glucagon-like peptide 2 receptor, GLP-2 receptor, GLP-2-R, GLP-2R, GLP2R |
| Host | mouse |
| Isotype | IgG2b Kappa |
| Form | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Specie Reactivity | WB, E |
| Image Legend | Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.84 KDa) . |
| References | Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Association study of 182 candidate genes in anorexia nervosa. Pinheiro AP, et al. Am J Med Genet B Neuropsychiatr Genet, 2010 Jul. PMID 20468064.Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121.Genetic analysis in a Dutch study sample identifies more ulcerative colitis susceptibility loci and shows their additive role in disease risk. Festen EA, et al. Am J Gastroenterol, 2010 Feb. PMID 19861958. |
| Image Link | View Document |
| View Document | |
| Note | The product is for research use only |
Share Item: