Human ACVR1B/Activin RIB Protein (ALK-HM204)
SKU: BTL-KB-P-00075 |
Host: Human |
Brand: Kactus Bio
Product Description
| Cat Number | ALK-HM204 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Human ACVR1B/Activin RIB Protein is expressed from HEK293 with hFc (IgG1) tag at the C-terminus.It contains Ser24-Glu126. |
| Target | ACVR1B/Activin RIB |
| Host | Human |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | Activin A receptor type I (ACVR1) encodes for a bone morphogenetic protein type I receptor of the TGFβ receptor superfamily. It is involved in a wide variety of biological processes, including bone, heart, cartilage, nervous, and reproductive system development and regulation. Moreover, ACVR1 has been extensively studied for its causal role in fibrodysplasia ossificans progressiva (FOP), a rare genetic disorder characterised by progressive heterotopic ossification. ACVR1 is linked to different pathologies, including cardiac malformations and alterations in the reproductive system. |
| Molecular Mass | The protein has a predicted MW of 37.36 kDa. Due to glycosylation, the protein migrates to 45-55 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Ser24-Glu126 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | P36896-1 |
| Amino Acid Sequence | Recombinant Human ACVR1B/Activin RIB Protein is expressed from HEK293 with hFc (IgG1) tag at the C-terminus.It contains Ser24-Glu126. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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