Product Description
| Cat Number | VK421036 |
|---|---|
| Category | Biosimilar |
| Pack Size | 100 ug |
| Description | Motavizumab(MEDI-524,NUMAX,NISTmAb)isasecondgenerationmonoclonalantibody(mAb)derivedfrompalivizumab(Synagis)usingaffinitymaturationtechniques.MotavizumabiscurrentlyundergoingUSFoodandDrugAdministrationreviewasatreatmentforrespiratorysyncytialvirus(RSV)prophylaxis.Ithasbeenevaluatedinlarge-scaleclinicalstudies,andhasdemonstratedefficacyinreducingthediseaseburdenofRSVinhigh-riskinfantpopulations.Motavizumab(MEDI-524,NUMAX,NISTmAb)hashigheraffinityandalongerhalf-life,waseffectiveinreducingRSVhospitalizationinhigh-riskfull-terminfantsintheUS,butwasnotlicensedduetosafetyconcerns(allergicreactions). |
| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| Target | F,FusionglycoproteinF0,FusionglycoproteinF2,p27,Interveningsegment,Pep27,Peptide27,FusionglycoproteinF1 |
| Clonality | Monoclonal |
| Synonyms | MEDI-524,NUMAX,NISTmAb,CR9503,CAS:677010-34-3 |
| Host | Humanized |
| Concentration | 2.8mg/ml |
| Isotype | IgG1,kappa |
| Form | Liquid |
| Purity | >95% as determined by SDS-PAGE. |
| Specie Reactivity | HRSV-A |
| Storage | 0.01M PBS, pH7.4. |
| Note | The product is for research use only |
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