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Peptain-1

SKU: BTL-IB-P-00287 | Brand: Isca Biochemical
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Product Description

Cat Number PP-520
Category Peptide
Pack Size 1 mg
Description Molecular chaperone
Modification None
Purity >95% by hplc
Biomarker Target Protein-protein interactions,Epitopes
Sequence Three Letter Code H-Asp-Arg-Phe-Ser-Val-Asn-Leu-Asp-Val-Lys-His-Phe-Ser-Pro-Glu-Glu-Leu-Lys-Val-Lys-Val-OH
Molecular Formula C113H180N30O33
Sl Sequence DRFSVNLDVKHFSPEELKVKV
Solubility Soluble in PBS
Appearance Freeze dried solid
Storage Store dry, frozen and in the dark
References Bhattacharyya et al (2006) Mini-alphaB-crystallin: a functional element of alphaB-crystallin with chaperone-like activity. Biochemistry 45(9) 3069 PMID: 16503662Nahomi et al (2013 Chaperone peptides of α-crystallin inhibit epithelial cell apoptosis, protein insolubilization, and opacification in experimental cataracts. J Biol Chem. 288(18) 13022 PMID: 23508955Stankowska et al (2019) Systemically administered peptain-1 inhibits retinal ganglion cell death in animal models: implications for neuroprotection in glaucoma. Cell Death Discov. 5 112 PMID: 31285855Nahomi et al (2019) A monoclonal antibody targeted to the functional peptide of αB-crystallin inhibits the chaperone and anti-apoptotic activities. J Immunol Methods. 467 37 PMID: 30738041
Related areas
All peptides >All epitopes >All protein-protein interaction modulators >All regulated cell death research categories >
Note The product is for research use only
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