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Pep63

SKU: BTL-IB-P-00284 | Brand: Isca Biochemical
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Product Description

Cat Number PP-500
Category Peptide
Pack Size 1 mg
Description EphB2 -  ADDL interaction inhibitor
Modification None
Purity >95% by hplc
Biomarker Target Protein-protein interactions
Sequence Three Letter Code H-Val-Phe-Gln-Val-Arg-Ala-Arg-Thr-Val-Ala-OH
Molecular Formula C51H87N17O13
Sl Sequence VFQVRARTVA
Solubility Soluble in saline
Appearance Freeze dried solid
Storage Store dry, frozen and in the dark
References Shi et al (2016) Blocking the Interaction between EphB2 and ADDLs by a Small Peptide Rescues Impaired Synaptic Plasticity and Memory Deficits in a Mouse Model of Alzheimer's Disease. J Neurosci. 36(47) 11959 PMID: 27881781Bruzzoni-Giovanelli (2018)  Interfering peptides targeting protein-protein interactions: the next generation of drugs? Drug Discov Today 23(2) 272 PMID: 29097277Yang (2021) Transferrin-Pep63-liposomes accelerate the clearance of Aβ and rescue impaired synaptic plasticity in early Alzheimer's disease models. Cell Death Discov. 7(1) 256 PMID: 34548476
Related areas
All peptides >All protein-protein interaction modulators >All neuroscience research categories >
Note The product is for research use only
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