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Tat-3L4F

SKU: BTL-IB-P-00368 | Brand: Isca Biochemical
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Product Description

Cat Number PP-490
Category Peptide
Pack Size 1 mg
Description 5-HTR2C - PTEN interaction disruptor
Modification None
Purity >95% by hplc
Biomarker Target Protein-protein interactions,Serotonin receptors
Sequence Three Letter Code H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Pro-Asn-Pro-Asp-Gln-Lys-Pro-Arg-Arg-Lys-Lys-Lys-Glu-Lys-Arg-OH
Molecular Formula C145H261N63O35
Sl Sequence YGRKKRRQRRRPNPDQKPRRKKKEKR
Solubility Soluble in 0.9% saline
Appearance Freeze dried solid
Storage Store dry, frozen and in the dark
References Ji et al (2006) Disruption of PTEN coupling with 5-HT2C receptors suppresses behavioral responses induced by drugs of abuse. 12(3) 324 PMID: 16474401Anastasio et al (2013) Peptide inhibitors disrupt the serotonin 5-HT2C receptor interaction with phosphatase and tensin homolog to allosterically modulate cellular signaling and behavior. J Neurosci. 33(4) 1615 PMID: 23345234Wang et al (2020) A Novel Synthetic Interfering Peptide Tat-3L4F Attenuates Olanzapine-Induced Weight Gain Through Disrupting Crosstalk Between Serotonin Receptor 2C and Protein Phosphatase and Tensin Homolog in Rats. Int J Neuropsychopharmacol. 23(8) 481 PMID: 32710540
Related areas
All cell penetrating peptides >All serotonergic receptor modulators >All protein-protein interaction modulators >All neuroscience research areas >
Note The product is for research use only
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