Product Description
| Cat Number | PP-120 |
|---|---|
| Category | Peptide |
| Pack Size | 1 mg |
| Description | PD-1/PD-L1 interaction inhibitor |
| Modification | Asn-1 = D-Asn, Tyr-2 = D-Tyr, Ser-3 = D-Ser, Lys-4 = D-Lys, Pro-5 = D-Pro, Thr-6 = D-Thr, Asp-7 = D-Asp, Arg-8 = D-Arg, Gln-9 = D-Gln, Tyr-10 = D-Tyr, His-11 = D-His, Phe-12 = D-Phe |
| Purity | >95% by hplc |
| Biomarker Target | Protein-protein interactions |
| Sequence Three Letter Code | H-(D)Asn-(D)Tyr-(D)Ser-(D)Lys-(D)Pro-(D)Thr-(D)Asp-(D)Arg-(D)Gln-(D)Tyr-(D)His-(D)Phe-OH |
| Molecular Formula | C70H98N20O21 |
| Sl Sequence | nyskptdrqyhf |
| Solubility | Soluble to 2 mg/ml in water |
| Appearance | Freeze dried solid |
| Storage | Store dry, frozen and in the dark |
| References |
Chang et al (2015) Blocking of the PD-1/PD-L1 interaction by a D-peptide antagonist for cancer immunotherapy. Angew Chem.Int.Ed.Engl. 54 11760 PMID: 26259671Sun et al (2018) PD-1/PD-L1 pathway and angiogenesis dual recognizable nanoparticles for enhancing chemotherapy of malignant cancer. Drug Deliv. 25(1) 1746 PMID: 30394118 Related areasAll peptides >All protein-protein interaction modulators >Cancer research categories > |
| Note | The product is for research use only |
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