Product Description
| Cat Number | PI-230 |
|---|---|
| Category | Peptide |
| Pack Size | 10 mg |
| Description | Dipeptidyl peptidase IV (DPP-IV) inhibitor |
| Purity | 98% by tlc |
| Biomarker Target | Dipeptidyl peptidase IV |
| Sequence Three Letter Code | 1-[2-[(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-2S-pyrrolidinecarbonitrile |
| Molecular Formula | C17H25N3O2 |
| Sl Sequence | 1-[2-[(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-2S-pyrrolidinecarbonitrile |
| Solubility | Soluble in water |
| Appearance | White solid |
| Storage | Store desiccated, frozen and in the dark |
| References |
Villhauer et al (2003) 1-[[(3-hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine: a potent, selective, and orally bioavailable dipeptidyl peptidase IV inhibitor with antihyperglycemic properties. J Med. Chem. 46(13) 2774 PMID: 12801240AhreÌn et al (2004) Inhibition of Dipeptidyl Peptidase-4 Reduces Glycemia, Sustains Insulin Levels, and Reduces Glucagon Levels in Type 2 Diabetes. J. Clin. Endocrinol. Metab. 89(5) 2078 PMID: 15126524Wu et al (2015) Dipeptidyl peptidase-4 inhibitor, vildagliptin, inhibits pancreatic beta cell apoptosis in association with its effects suppressing endoplasmic reticulum stress in db/db mice. Metabolism 64(2) 226 PMID: 25195070 Related areasAll small molecules >All dipeptidyl peptidase IV modulators >All diabetes research categories > |
| Note | The product is for research use only |
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