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PR 619

SKU: BTL-IB-P-00304 | Brand: Isca Biochemical
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Product Description

Cat Number PI-150
Category Peptide
Pack Size 5 mg
Description Broad spectrum deubiquitinylating enzyme (DUB) inhibitor
Purity >98% by hplc
Biomarker Target Deubiquitinating enzymes
Sequence Three Letter Code 2,6-Diamino-3,5-dithiocyanopyridine
Molecular Formula C7H5N5S2
Sl Sequence 2,6-Diamino-3,5-dithiocyanopyridine
Solubility Soluble to 10 mM in DMSO
Appearance Light brown solid
Storage Store desiccated, frozen and in the dark
References Altun et al (2011) Activity-based chemical proteomics accelerates inhibitor development for deubiquitylating enzymes. Chem.Biol. 18 1401 PMID: 22118674Seiberlich et al (2012) The small molecule inhibitor PR-619 of deubiquitinating enzymes affects the microtubule network and causes protein aggregate formation in neural cells: implications for neurodegenerative diseases. Biochim.Biophys.Acta 1823 2057 PMID: 22565157
Related areas
All small molecules >All deubiquitinating enzyme modulators >All cancer research areas >
Note The product is for research use only
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