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Phosphoramidon disodium

SKU: BTL-IB-P-00295 | Brand: Isca Biochemical
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Product Description

Cat Number PI-130
Category Peptide
Pack Size 5 mg
Description Metalloendopeptidase inhibitor
Modification N-(α-Rhamnopyranosyloxyhydroxyphosphinyl at N terminal
Purity ‰¥97% (HPLC)
Biomarker Target Matrix metalloproteases,Other proteases
Sequence Three Letter Code N-(α-Rhamnopyranosyloxyhydroxyphosphinyl)-L-leucyl-L-tryptophan
Molecular Formula C23H32N3O10P€¢2Na
Sl Sequence LW
Solubility 50 mg per ml in water
Appearance Off white powder
Storage Store desiccated, frozen and in the dark
References Bao et al (2016) Deacetylation of TFEB promotes fibrillar Aβ degradation by upregulating lysosomal biogenesis in microglia. Protein Cell 7(6) 417 PMID: 27209302Goblirsch et al (2018) Phosphoramidon inhibits the integral membrane protein zinc metalloprotease ZMPSTE24. Acta. Crystallogr. D Struct. Biol. 74(Pt 8) 739 PMID: 30082509Li et al (2018) SIRT1 facilitates amyloid beta peptide degradation by upregulating lysosome number in primary astrocytes. Neural Regen. Res. 13(11) 2005 PMID: 30233076
Related areas
All small molecules >All matrix metalloprotease modulators >
Note The product is for research use only
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