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PS18

SKU: BTL-IB-P-00307 | Brand: Isca Biochemical
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Product Description
Cat Number OR-040
Category Peptide
Pack Size 1 mg
Description Neurotrophic and neuroprotective 
Modification None
Purity >95% by hplc
Biomarker Target Orphan 7-TM receptors
Sequence Three Letter Code H-Leu-Ser-Glu-Leu-Ile-Ile-Asn-Asn-Ala-Thr-Glu-Glu-Leu-Leu-Ile-Lys-Gly-Leu-OH
Molecular Formula C89H155N21O29
Sl Sequence LSELIINNATEELLIKGL
Solubility Soluble in water
Appearance Freeze dried solid
Storage Store dry, frozen and in the dark
References Kotani et al (1996) A hydrophilic peptide comprising 18 amino acid residues of the prosaposin sequence has neurotrophic activity in vitro and in vivo. J Neurochem. 66(5) 2197 PMID: 8780053Nabeka et al (2015) A prosaposin-derived Peptide alleviates kainic Acid-induced brain injury. PLoS One 10(5) e0126856 PMID: 25993033Gao et al (2016) An 18-mer Peptide Derived from Prosaposin Ameliorates the Effects of Aβ1-42 Neurotoxicity on Hippocampal Neurogenesis and Memory Deficit in Mice. J Alzheimers Dis. 53(3) 1173 PMID: 27372641Wu (2023) Prosaposin PS18 reduces dopaminergic neurodegeneration in a 6-hydroxydopamine rat model of Parkinson's disease. Sci Rep. 13(1) 8148 PMID: 37208379
Related areasAll peptides >All orphan 7-TM receptor modulators >All neuroscience research categories >
Note The product is for research use only
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