[cPP1-7,NPY19-23,Ala31,Aib32,Gln34] - hPancreatic polypeptide
SKU: BTL-IB-P-00430 |
Brand: Isca Biochemical
Product Description
| Cat Number | NY-010 |
|---|---|
| Category | Peptide |
| Pack Size | 1 mg |
| Description | Potent and selective Y5 agonist |
| Modification | X = Aib, Tyr-36 = C-terminal amide |
| Purity | >95% by hplc |
| Biomarker Target | Neuropeptide Y receptors |
| Sequence Three Letter Code | H-Gly-Pro-Ser-Gln-Pro-Thr-Tyr-Pro-Gly-Asp-Asn-Ala-Thr-Pro-Glu-Gln-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-Arg-Tyr-Ile-Asn-Met-Ala-Aib-Arg-Gln-Arg-Tyr-NH2 |
| Molecular Formula | C183H281N57O54S2 |
| Sl Sequence | GPSQPTYPGDNATPEQMARYYSALRRYINMAXRQRY-NH2 |
| Solubility | Soluble to 1 mg/ml in water |
| Appearance | Freeze dried solid |
| Storage | Store dry, frozen and in the dark |
| References |
Cabrele et al (2000) The first selective agonist for the neuropeptide YY5 receptor increases food intake in rats. J.Biol.Chem. 275 36043 PMID: 10944518Quarta et al (2011) Central administration of NPY or an NPY-Y5 selective agonist increase in vivo extracellular monoamine levels in mesocorticolimbic projecting areas. Neuropharmacology 60(2-3) 328 PMID: 20868698Medeiros and Jackson (2013) Neuropeptide Y Y5-receptor activation on breast cancer cells acts as a paracrine system that stimulates VEGF expression and secretion to promote angiogenesis. Peptides 48 106 PMID: 23932937 Related areas All peptides >All neuropeptide Y receptor modulators >All appetite regulation research categories > |
| Note | The product is for research use only |
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