Product Description
| Cat Number | NO-010 |
|---|---|
| Category | Peptide |
| Pack Size | 1 mg |
| Description | Potent and selective nociceptin receptor antagonist |
| Modification | N-terminal benzyl, C-terminal amide |
| Purity | >95% by hplc |
| Biomarker Target | Nociceptin receptors |
| Sequence Three Letter Code | Bn-Gly-Gly-Gly-Phe-Thr-Gly-Ala-Arg-Lys-Ser-Ala-Arg-Lys-Arg-Lys-Asn-Gln-NH2 |
| Molecular Formula | C82H138N32O21 |
| Sl Sequence | Bn-GGGFTGARKSARKRKNQ-NH2 |
| Solubility | Soluble to 1 mg/ml in water |
| Appearance | Freeze dried solid |
| Storage | Store dry, frozen and in the dark |
| References |
Calo et al (2002) [Nphe1,Arg14,Lys15]Nociceptin-NH2, a novel potent and selective antagonist of the nociceptin/orphanin FQ receptor. Br.J.Pharmacol. 136 303 PMID: 12010780Calo et al (2005) UFP-101, a peptide antagonist selective for the nociceptin/orphanin FQ receptor. CNS Drug Rev. 11(2) 97 PMID: 16007234Brookes et al (2013) The nociceptin/orphanin FQ receptor antagonist UFP-101 reduces microvascular inflammation to lipopolysaccharide in vivo. PLoS One 8(9) e74943 PMID: 24086402 Related areas_x000D_ All peptides >All nociceptin receptor modulators >All pain research categories >All neuroscience research categories > |
| Note | The product is for research use only |
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