Product Description
| Cat Number | NMB001 |
|---|---|
| Category | Peptide |
| Pack Size | 0.1 mg |
| Description | NMB-1 (Noxious mechanosensation blocker 1) is an analogue of a peptide isolated from a marine conesnail. This 19 amino acid peptide has shown a 30 fold selectivity in inhibiting slowly adapting mechanically activated currents over rapidly adapting ones. It is an interesting tool to distinguish between RA and SA currents. NMB-1 significantly blocks SA currents at 1 µM in sensory neurons contrary to GsMTx4. Some results suggest that NMB-1 could also block mechanosensitive ion channels in cochlear hair cells at 5 µM. Smartox Biotechnology is pleased to be the first company offering this research tool. |
| C Ter | OH |
| Disulfide Bonds | Cys5-Cys19; Cys6-Cys10 |
| Note | The product is for research use only |
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