Product Description
| Cat Number | LED01 |
|---|---|
| Category | Peptide |
| Pack Size | 0.1 mg |
| Description | Leiuorotoxin-Dab7 (Lei-Dab7) is a mutated version of Leiurotoxin, a peptide identified from the venom of the scorpion Leiurus quinquestriatus hebraeus. The Dab amino acid in position 7 confers to this compound a high selectivity for SK2 channels among other channels. Lei-Dab7 exhibits > 200 fold selectivity for SK2 over SK1, SK3, IK, Kv and Kir channels. The IC50 for SK2 is about 3 nM. |
| C Ter | NH2 |
| Disulfide Bonds | Cys3-Cys21; Cys8-Cys26; Cys12-Cys28 |
| Note | The product is for research use only |
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