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Autocamtide-2-related inhibitory peptide

SKU: BTL-IB-P-00055 | Brand: Isca Biochemical
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Product Description
Cat Number KS-190
Category Peptide
Pack Size 1 mg
Description CaM kinase II inhibitor
Modification None
Purity >95% by hplc
Biomarker Target Kinases
Sequence Three Letter Code H-Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Ala-Val-Asp-Ala-Leu-OH
Molecular Formula C64H116N22O19
Sl Sequence KKALRRQEAVDAL
Solubility Soluble to 1 mg/ml in water
Appearance Freeze dried solid
Storage Store dry, frozen and in the dark
References Ishida et al (1995) A novel highly specific and potent inhibitor of calmodulin-dependent protein kinase II. Biochem.Biophys.Res.Commun. 212 806 PMID: 7626114Wagner et al (2006) Ca2+/calmodulin-dependent protein kinase II regulates cardiac Na+ channels.  J Clin Invest. 116(12) 3127 https://doi.org/10.1172/JCI26620.Ikeda et al (2019) Blockade of L-type Ca2+ channel attenuates doxorubicin-induced cardiomyopathy via suppression of CaMKII-NF- κ B pathway. Sci Rep 9 9850  https://doi.org/10.1038/s41598-019-46367-6Feng et al (2023) The CaMKII Inhibitory Peptide AIP Alleviates Renal Fibrosis Through the TGF-β/Smad and RAF/ERK Pathways. J Pharmacol Exp Ther. 386(3) 310 PMID: 37419684
Related areas All peptides >All kinase modulators >All cardiovascular research categories >
Note The product is for research use only
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