Product Description
| Cat Number | GJ-040 |
|---|---|
| Category | Peptide |
| Pack Size | 1 mg |
| Description | Connexin43 hemichannel inhibitor |
| Modification | None |
| Purity | >95% by hplc |
| Biomarker Target | Gap junction channels |
| Sequence Three Letter Code | H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Lys-Gln-Ile-Glu-Ile-Lys-Lys-Phe-Lys-OH |
| Molecular Formula | C119H212N46O26 |
| Sl Sequence | YGRKKRRQRRRKQIEIKKFK |
| Solubility | Soluble to 1 mg/ml in water |
| Appearance | Freeze dried solid |
| Storage | Store dry, frozen and in the dark |
| References |
Abudara et al (2014) The connexin43 mimetic peptide Gap19 inhibits hemichannels without altering gap junctional communication in astrocytes. Front.Cell.Neurosci. 8 1 PMID: 25374505Crespo et al (2018) TAT-Gap19 and Carbenoxolone Alleviate Liver Fibrosis in Mice. Int J Mol Sci. 9(3) 817 PMID: 29534516Ramadan (2020) Connexin43 Hemichannel Targeting With TAT-Gap19 Alleviates Radiation-Induced Endothelial Cell Damage. Front Pharmacol. 11 212 PMID: 32210810 Related areasAll cell penetrating peptides >All gap junction channel modulators >All immunology research categories > |
| Note | The product is for research use only |
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