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TransDetect® In Situ Click TUNEL Imaging Kit-488 Fluorophore

SKU: BTL-TB-MB-00534 | Brand: Transgen Biotek
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Product Description

Cat Number FA301-02
Category Molecular Biology Product
Pack Size 50 rxns
Description TransDetect® In Situ Click TUNEL Imaging Kit-488 Fluorophore is a TUNEL assay reagent based on the Click reaction. In apoptosis, double-strand breaks or single strand breaks of genomic DNA can produce a large number of sticky 3'-OH ends. EdUTP is a dUTP nucleotide modified with a small alkyne moiety, which is more readily incorporated at the 3´-OH ends of fragmented DNA by the Terminal deoxynucleotidyl transferase (TdT) enzyme. A covalent reaction occurs between the azide and the alkyne moiety on EdUTP based on the Click reaction, and more sensitive TUNEL detection can be performed via fluorophore on the azide. Storage at -20˚C in the dark for one year Shipping Dry ice (-70℃)
Note The product is for research use only
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