Product Description
| Cat Number | CS-010 |
|---|---|
| Category | Peptide |
| Pack Size | 1 mg |
| Description | Cell-permeable, irreversible caspase-3 inhibitor |
| Modification | Asp-1 = Z-Asp(OMe), Glu-2 = Glu(OMe), Asp-4 = (OMe)-fluoromethylketone |
| Purity | >95% by hplc |
| Biomarker Target | Caspases |
| Sequence Three Letter Code | Benzyloxycarbonyl-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-fluoromethylketone |
| Molecular Formula | C30H41FN4O12 |
| Sl Sequence | DEVD |
| Solubility | Soluble in DMSO |
| Appearance | Freeze dried solid |
| Storage | Store dry, frozen and in the dark |
| References |
Ma et al (1998) Synergistic effects of caspase inhibitors and MK-801 in brain injury after transient focal cerebral ischaemia in mice. Br J Pharmacol. 124(4) 756 PMID: 9690868Henshall et al (2000) Involvement of caspase-3-like protease in the mechanism of cell death following focally evoked limbic seizures. J.Neurochem. 74 1215 PMID: 10693954Barut et al (2005) The neuroprotective effects of z-DEVD.fmk, a caspase-3 inhibitor, on traumatic spinal cord injury in rats. Surg Neurol. 64(3) 213 PMID: 16099247 Related areas_x000D_ All peptides >All caspase modulators >All neuroscience research categories > |
| Note | The product is for research use only |
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