Product Description
| Cat Number | CRO002 |
|---|---|
| Category | Peptide |
| Pack Size | 0.1 mg |
| Description | Cy3-crotamine is a fluorescent version of Crotamine which is a basic peptide present in the venom of the South American rattlesnake Crotalus durissus terrificus. Multiple biological functions have been attributed to Crotamine. It is a natural cell-penetrating peptide with selective biological action towards actively proliferating cell types such as tumor cells. Moreover, it has been reported that crotamine is a blocker of Kv1.3 (IC50 around 300 nM) as well as Kv1.1 and Kv1.2. It has analgesic properties and myonecrotic effects. In addition, crotamine belongs to the beta-defensin peptides and as such demonstrates antibacterial properties by interacting with lipid membranes. |
| C Ter | OH |
| Disulfide Bonds | Cys4-Cys36; Cys11-Cys30; Cys18-Cys37 |
| Note | The product is for research use only |
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