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Biotinylated Mouse MDL-1/CLEC5A Protein (CLE-MM45AB)

SKU: BTL-KB-P-01054 | Host: Mouse | Brand: Kactus Bio
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Product Description

Cat Number CLE-MM45AB
Category Recombinant Protein
Pack Size 100UG
Description Recombinant Biotinylated Mouse MDL-1/CLEC5A Protein is expressed from HEK293 with His tag and Avi tag at the N-terminus.It contains Tyr26-Lys190.
Target MDL-1/CLEC5A
Host Mouse
Purity > 95% as determined by Bis-Tris PAGE
Scientific Background In C. elegans, increased lifespan in daf-2 insulin/IGF-1 receptor mutants is accompanied by up-regulation of the MDL-1 Mad basic helix-loop-helix leucine zipper transcription factor.MDL-1, like its mammalian orthologs, is an inhibitor of cell proliferation and growth that slows progression of an age-related pathology in C. elegans (uterine tumors). In addition, intestine-limited rescue of mdl-1 increased lifespan but not to wild type levels. Thus, mdl-1 likely acts both in the intestine and the germline to influence age-related mortality.
Molecular Mass The protein has a predicted MW of 21.76 kDa. Due to glycosylation, the protein migrates to 35-50 kDa based on Bis-Tris PAGE result.
Sl Sequence Tyr26-Lys190
Solubility Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Appearance Lyophilized
Endotoxin Levels Less than 1 EU per μg by the LAL method.
Expression System HEK293
Gene Id Q9R007-3
Amino Acid Sequence Recombinant Biotinylated Mouse MDL-1/CLEC5A Protein is expressed from HEK293 with His tag and Avi tag at the N-terminus.It contains Tyr26-Lys190.
Storage -20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3 months after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Pdf View Document
Note The product is for research use only
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