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Rimonabant

SKU: BTL-IB-P-00319 | Brand: Isca Biochemical

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Product Description

Cat Number	CB-020
Category	Peptide
Pack Size	10 mg
Description	CB1 receptor inverse agonist
Purity	> 98% by hplc, NMR conforms
Biomarker Target	μ Opioid receptors,Cannabinoid receptors
Sequence Three Letter Code	5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-piperidin-1-yl-1H-pyrazole-3-carboxamide
Molecular Formula	C22H21Cl3N4O
Solubility	Soluble in DMSO to 20 mg/ml or ethanol to 20 mg/ml
Appearance	White solid
Storage	Store dry, frozen and in the dark
References	Rinaldi-Carmona et al (1995) Biochemical and pharmacological characterisation of SR141716A, the first potent and selective brain cannabinoid receptor antagonist. Life Sci. 56(23-24) 1941 PMID: 7776817Colombo et al (1998) Appetite suppression and weight loss after the cannabinoid antagonist SR 141716. Life Sci. 63(8) PL113-7 PMID: 9718088Boyd and Fremming (2005) Rimonabant--a selective CB1 antagonist. Ann Pharmacother. 39(4) 684 PMID: 15755787Seely et al (2012) AM-251 and rimonabant act as direct antagonists at mu-opioid receptors: implications for opioid/cannabinoid interaction studies. Neuropharmacology 63(5) 905 PMID: 22771770Bosquez-Berger et al (2023) A. Requiem for Rimonabant: Therapeutic Potential for Cannabinoid CB1 Receptor Antagonists after the Fall. Drugs Drug Candidates 2 689 https://doi.org/10.3390/ddc2030035 Related areas All small molecules >All cannabinoid receptor modulators >All μ opioid receptor modulators >All neuroscience research categories >All appetite regulation research categories >
Note	The product is for research use only

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