Product Description
| Cat Number | 12GSF001 |
|---|---|
| Category | Peptide |
| Pack Size | 0.1 mg |
| Description | GsAF-1 (also termed β-theraphotoxin-Gr1b, GsAF-I) was originally isolated from the venom of Grammostola rosea spider. GsAF-I peptide toxin is reported to block the following voltage-gated sodium channel isoforms: Nav1.1, Nav1.2, Nav1.3, Nav1.4, Nav1.6 and Nav1.7 with respective IC50 values of 0.4, 0.6, 1.3, 0.3, 1.2 and 0.04 µM. In addition, the toxin blocks the hERG1 isoform with an IC50 value of 4.8 µM. |
| C Ter | NH2 |
| Disulfide Bonds | Cys2-Cys16; Cys9-Cys21; ; Cys15-Cys25 |
| Note | The product is for research use only |
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