Product Description
| Cat Number | 08SHK001 |
|---|---|
| Category | Peptide |
| Pack Size | 0.1 mg |
| Description | ShK (Stichodactyla helianthus Neurotoxin) has been isolated from the venom of the Carribean sea anemone Stoichactis helianthus. ShK inhibits voltage-dependent potassium channels. It blocks Kv1.3 (KCNA3) potently and also Kv1.1 (KCNA1), Kv1.4 (KCNA4) and Kv1.6 (KCNA6) respectively with a Kd of 11 pM, 16 pM, 312 pM and 165 pM. Interestingly, it was also demonstrated that ShK potently inhibits the hKv3.2b channel with an IC50 value of approximately 0.6 nM |
| C Ter | OH |
| Disulfide Bonds | Cys3-Cys35; Cys12-Cys28; Cys17-Cys32 |
| Note | The product is for research use only |
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