Product Description
| Cat Number | 08CON009 |
|---|---|
| Category | Peptide |
| Pack Size | 0.5 mg |
| Description | Conantokin-G is a conopeptide that has been isolated from the venom of the cone Conus geographus. Conantokin-G selectively inhibits NR2B containing N-methyl-D-aspartate receptors (NMDAR) with a high specificity. Thus, Conantokin-G inhibits in a concentration-dependent manner the Ca2+ influx leading to a neuroprotective effect against NMDA-induced excitotoxicity. Conantokin-G was shown to block NMDA-evoked currents in murine cortical neurons with an IC50 value of around 480 nM. |
| C Ter | NH2 |
| Disulfide Bonds | _ |
| Note | The product is for research use only |
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