Product Description
| Cat Number | 08CON002 |
|---|---|
| Category | Peptide |
| Pack Size | 0.1 mg |
| Description | ω-conotoxin MVIIC (omega conotoxin MVIIC) is a conotoxin that has been isolated from the venom of the cone Conus magus. ω-conotoxin MVIIC is a blocker of P/Q (IC50=35 nM) and N-type calcium channels. It inhibits presynaptic Ca2+ channels, including the Ca2+ channels responsible for Ca2+ uptake by rat brain synaptosomes, the P-type Ca2+ channels in cerebellar Purkinje cells, and a significant fraction of ω-conotoxin GVIA-resistant currents in hippocampal CA1 neurons. ω-conotoxin MVIIC also presents an inhibition of ω-conotoxin GVIA-resistant depolarization-induced neurotransmitter release in cerebellar neurons of rats. |
| C Ter | NH2 |
| Disulfide Bonds | Cys1-Cys16; Cys8-Cys20; Cys15-Cys26 |
| Note | The product is for research use only |
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